DART® mass spectrometry, rapid analysis of soft medicinal formulations

Authors: Elena S. Chernetsova, Rimma A. Abramovich
Pharmaceutical Chemistry Journal 2012, Mar, 15, 45(11), 1-3
10.1007/s11094-012-0705-4

 

The possibility of using the DART® mass spectrometry method for rapid analysis of soft medicinal formulations is considered. Studies of “tetracycline”, “Sintomycin Liniment”, and “Levomecol” creams and suppositories based on hard fat were studied. The possibility of using this method for the rapid screening of medicinal formulations in search of counterfeits is discussed. This is the first report of the analysis of suppositories using DART® mass spectrometry.