Tylenol Cold Tablet

2010, Nov, 04

 

Content Data and Images

 

Nighttime Caplet
– Acetaminophen
• 325 mg/caplet
– Phenylephrine HCl
• 5 mg/caplet
– Chlorpheniramine
Maleate
• 2 mg/caplet

10% Tylenol Powder in Metal
• TIC irregular
• Mass chromatogram for each API’s have consistent ratios
– Acetaminophen = A
– Phenylephrine = P
– Chlorpheniramine
Maleate = C
• Relative abundance vary from sample to sample

1% Tylenol Powder in Metal
• TIC more uniform
• Mass spectrum at lower temp 350C shows reduced C
Acetaminophen = A
Phenylephrine = P
Chlorpheniramine Maleate = C