The DART-HT enables the use of automated liquid handlers to deposit directly onto the new QuickStrip-96 consumable allowing integration of the device into the laboratory workflow and sample informatics. Sample deposited onto each of the discrete screen positions analyzed by moving the screen into position between the front of the DART® source and the inlet of the mass spectrometer under control of the SVP software. This high throughput application of DART® technology eliminates the need for chromatography, thus, simplifying sample prep and speeding analysis.