Publications

Ambient Ionization–Accurate Mass Spectrometry (AMI-AMS) for the Identification of Nonvisible Set-off in Food-Contact Materials

Authors: Luke Ackerman, Timothy Begley, Karim Bentayeb
J. Agric. Food Chem. 2012, Jan, 17, 60 (8), 1914–1920
10.1021/jf204456z
 
Set-off is the unintentional transfer of substances used in printing from the external printed surface of food packaging to the inner, ...

Sensitivity “Hot Spots” in the Direct Analysis in Real Time Mass Spectrometry of Nerve Agent Simulants

Authors: Glenn Harris, Facundo Fernndez
Journal of The American Society for Mass Spectrometry 2012, Jan, 01, 23(1), 153-161
10.1007/s13361-011-0276-8
 
Presented here are findings describing the spatial-dependence of sensitivity and ion suppression effects observed with direct analysis in ...

Rapid qualitative analysis of phthalates added to food and nutraceutical products by direct analysis in real time orbitrap mass spectrometry

Authors: Randy L. Self, Wen-Hsin Wu
Food Control 2011, Oct, 18, 25(1), 13–16
10.1016/j.foodcont.2011.10.013
 
A recent food safety issue involves the contamination of a broad range of food and nutraceutical products from Taiwan with industrial ...

Validation of Thin Layer Chromatography with AccuTOF-DART® Detection for Forensic Drug Analysis

Authors: Robert R. Steiner
Journal of Forensic Sciences 2011, Sep, 01, 56(5), 1261–1267
10.1111/j.1556-4029.2011.01881.x
 
Thin layer chromatography (TLC) is a technique that is commonly employed in the forensic drug analysis of pharmaceutical preparations. ...

Rapid identification and absence of drug tests for AG-013736 in 1 mg Axitinib tablets by ion mobility spectrometry and DART® mass spectrometry

Authors: Michael D. Likar, Guilong Cheng, Nidhi Mahajan, Zhongli Zhang
Journal of Pharmaceutical and Biomedical Analysis 2011, Jun, 01, 55(3), 569–573
10.1016/j.jpba.2011.02.021
 
Axitinib (AG-013736) is a potent investigational drug that has antitumor activity in patients with metastatic renal cell carcinoma and ...

Rapid screening for synthetic antidiabetic drug adulteration in herbal dietary supplements using direct analysis in real time mass spectrometry

Authors: Zhigui Zhou, Jialing Zhang, Wei Zhang, Yu Bai, Huwei Liu
Analyst 2011, May, 03, Issue 12, 136, 2613-2618
10.1039/C0AN01047B
 
Adulteration of herbal supplements with synthetic drugs is illegal. A rapid and reliable method which utilizes direct analysis in real time ...

New approach to detecting counterfeit drugs in tablets by DART® mass spectrometry

Authors: Elena S. Chernetsova, Pavel O. Bochkov, Rimma A. Abramovich
PHARMACEUTICAL CHEMISTRY JOURNAL 2011, May, 01, 45(5), 306-308
10.1007/s11094-011-0622-y
 
The possibility of using DART® mass spectrometry for the identification of active ingredients in tableted drugs has been studied. ...

Direct Analysis in Real Time Coupled to Multiplexed Drift Tube Ion Mobility Spectrometry for Detecting Toxic Chemicals

Authors: Glenn Harris, Facundo Fernndez, Mark Kwasnik
Anal Chem 2011, Mar, 15, 83(6), 1908-15
10.1021/ac051277q
 
Current and future chemical threats to homeland security motivate the need for new chemical detection systems to provide border, ...

Ricin Activity Assay by Direct Analysis in Real Time Mass Spectrometry Detection of Adenine Release

Authors: Vicky Bevilacqua , J. Michael Nilles, Jeffrey Rice, Theresa Connell, Amanda Schenning, Lisa Reilly
Analytical Chemistry 2010, Dec, 10, 83(3), 798-800
10.1021/ac9025972
 
Biotoxin activity assays typically involve multistep sample preparation, multicomponent reactions, multistep analysis, or a combination ...

DART®–TOFMS A CHALLENGING APPROACH IN RAPID MONITORING OF BROMINATED FLAME RETARDANTS IN ENVIRONMENTAL MATRICES

Authors: Jana Hajslova , Pulkrabova Jana, Jan Poustka, Cajka Tomas, Lukas Vaclavik
Organohalogen Compounds 2010, Dec, 10, 70, 00092- 00092
 
Introduction :
In the past few years, ambient desorption ionization mass spectrometry has become a rapidly growing technique,

Explosives Detection Using Direct Analysis in Real Time (DART®) Mass Spectrometry

Authors: J. Michael Nilles, Theresa Connell, H. Dupont Durst, Sarah T. Stokes
Propellants, Explosives, Pyrotechnics 2010, Jun, 30, 35(5), 446 - 451
10.1002/prep.200900084
 
Abstract The growing use of explosives by terrorists and criminals creates a need for instrumentation which can rapidly analyze these ...

Identification of a cannabimimetic indole as a designer drug in a herbal product

Authors: Noriko Uchiyama
2010, Jun, 24, ,
 
Forensic Toxicology, 2009. 27(2):p. 61-66.

DOI: 10.1007/s11419-009-0069-y

A cannabimimetic indole has been identified ...

Development and validation of AccuTOF-DART® as a screening method for analysis of bank security device and pepper spray components

Authors: Allison Pfaff, Robert R. Steiner
Forensic Science International. 2010, Jun, 18, Article in Press,
doi:10.1016/j.forsciint.2010.06.018
 
Analysis of bank security devices, containing 1-
methylaminoanthraquinone (MAAQ) and o-chlorobenzylidenemalononitrile
(CS), and ...

A Rapid Technique for the Confirmation of Iodine and Red Phosphorus Using Direct Analysis in Real Time and Accurate Mass Spectrometry

Authors: Robert R. Steiner
Microgram Journal 2010, Mar, 01, 7(1), 3-6
 
Iodine and red phosphorus are chemicals commonly seen in clandestine methamphetamine laboratories. Current analytical methods used for the ...

An Improved Protocol for the Analysis of Alcohols by Direct Analysis in Real Time Mass Spectrometry

Authors: J. Michael Nilles, Theresa Connell, H. Dupont Durst, James A. Laramée
American Laboratory 2009, Jun, 18, 41, 25-27
 
It was previously reported1 that when Direct Analysis in Real Time (DART®™) (JEOL USA, Inc., Peabody, MA) mass spectrometry was applied ...

Alcohols Can Now Be Analyzed by a Direct Analysis in Real-Time Method, Applications for Chemical Warfare Agent Synthesis

Authors: J. Michael Nilles, Theresa Connell, H. Dupont Durst, James A. Laramée
American Laboratory 2009, Mar, 01, 41, 24-27
 
The cardinal principle for an operation involving chemical agents is to limit the potential exposure to a minimum number of personnel, for ...

Detection of Peroxide and Tetrazine Explosives on Surfaces by Direct Analysis in Real Time Mass Spectrometry

Authors: J. Michael Nilles, Theresa Connell, H. Dupont Durst, James A. Laramée
American Laboratory Online Edition 2009, Jan, 01, 2, 1-5
 

AccuTOF-DART® has completely changed the field of mass spectrometry. Now you can immediately determine chemical composition and ...


Detection of Chemical Warfare Agents on Surfaces Relevant to Homeland Security by Direct Analysis in Real-Time Spectrometry

Authors: J. Michael Nilles, Theresa Connell, H. Dupont Durst, James A. Laramée
American Laboratory 2008, Sep, 01, 40, 16-20
 
Unlike other analytical methods that necessitate that the surface be sprayed with electrically charged solvents, or that require solvent ...

Forensic Application of DART® (Direct Analysis in Real Time) Mass Spectrometry

Authors: H. Dupont Durst, James A. Laramée, Robert B. Cody, Michael Nilles
Book Title Forensic Analysis on the Cutting Edge: New Methods for Trace Evidence Analysis 2007, Jan, 01, ,
10.1002/9780470166932.ch7
 

Chemi-ionization and Direct Analysis in Real Time (DART®) Mass Spectrometry

Authors: James A. Laramée, Robert B. Cody, Richard M. Caprioli
The Encyclopedia of Mass Spectrometry Volume 6: Ionization Methods 2007, Jan, 01, , 377-387